BVP models: An adjustment to express a mechanism of inactivation
- 1 August 1982
- journal article
- research article
- Published by Springer Nature in Biological Cybernetics
- Vol. 44 (3) , 223-229
- https://doi.org/10.1007/bf00344278
Abstract
Fitzhugh's BVP model has been used by many people. Fitzhugh has pointed out that as the stimulus is increased the model has “inverted” behaviour. It is here shown that this is due to a lack of a mechanism of inactivation, and the model is adjusted by supplying such a mechanism, to give a new model, called BPH, which, like Fitzhugh's, is of second order, with one equation of first degree and the other of third degree in the dynamical variables. Numerical solutions of the new system are compared with numerical solutions of the Hodgkin-Huxley and of the Fitzhugh equations.Keywords
This publication has 22 references indexed in Scilit:
- Numerical calculation of stable and unstable periodic solutions to the Hodgkin-Huxley equationsMathematical Biosciences, 1980
- Boundary value problems for the Fitzhugh-Nagumo equationsJournal of Differential Equations, 1978
- Bifurcation of periodic solutions of the Hodgkin-Huxley model for the squid giant axonJournal of Theoretical Biology, 1978
- Qualitative theory of the FitzHugh-Nagumo equationsAdvances in Mathematics, 1978
- A theory of synchronization of heart pace-maker cellsJournal of Theoretical Biology, 1976
- A stochastic analysis of the graded excitatory response of nerve membraneJournal of Theoretical Biology, 1976
- ON THE EXISTENCE OF HOMOCLINIC AND PERIODIC ORBITS FOR THE FITZHUGH-NAGUMO EQUATIONSThe Quarterly Journal of Mathematics, 1976
- Nagumo's equationAdvances in Mathematics, 1970
- Digital computer solutions for excitable membrane modelsJournal of Cellular and Comparative Physiology, 1965
- Impulses and Physiological States in Theoretical Models of Nerve MembraneBiophysical Journal, 1961