The Relation Between Chemical Structure and Uncoupling Activity in Congeners of Salicylate
- 1 September 1961
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 13 (1) , 65-71
- https://doi.org/10.1111/j.2042-7158.1961.tb11789.x
Abstract
The relation between chemical structure and uncoupling activity in congeners of salicylate has been studied by means of their effects on the oxygen consumption of a suspension of baker's yeast utilising a limited quantity of glucose. Salicylic acid, salicylaldehyde, 2-hydroxyacetophenone, salicylamide, 3-methylsalicylic and 1-hydroxy-2-naphthoic acids were found to show uncoupling activity.Keywords
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