Canine gastric and pancreatic secretion during intestinal distension and intestinal perfusion with choline derivatives

Abstract
Balloon distension of the duodenum in conscious dogs increased gastric acid secretion, but had no effect on external pancreatic secretion. Duodenal infusion of solutions of acetylcholine chloride did not stimulate pancreatic secretion. Duodenal infusion of solutions of bethanechol stimulated both gastric acid secretion and pancreatic secretion, but the same doses of bethanechol were more effective secretory stimulants when introduced intravenously.

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