Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo
- 25 April 2008
- journal article
- research article
- Published by Elsevier in Neuroscience Letters
- Vol. 435 (3) , 186-189
- https://doi.org/10.1016/j.neulet.2008.02.032
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Levels Become Elevated in Neurons around Amyloid Plaques: Implications for Alzheimer's Disease PathogenesisJournal of Neuroscience, 2007
- Bace1 modulates myelination in the central and peripheral nervous systemNature Neuroscience, 2006
- Control of Peripheral Nerve Myelination by the ß-Secretase BACE1Science, 2006
- BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild‐type mice2Journal of Neurochemistry, 2006
- BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic FunctionsJournal of Neuroscience, 2005
- NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β ProductionJournal of Neuroscience, 2005
- Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient MiceJournal of Biological Chemistry, 2005
- Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2Journal of Neuroscience, 2005
- The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to TherapeuticsScience, 2002
- Increased expression of the amyloid precursor β‐secretase in Alzheimer's diseaseAnnals of Neurology, 2002