Localization of Carbonic Anhydrase in the Nervous System
- 10 November 1961
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 134 (3489) , 1524-1525
- https://doi.org/10.1126/science.134.3489.1524
Abstract
Single-cell analyses of carbonic anhydrase demonstrate that this enzyme is selectively concentrated in the glial and choroid cells of the rat brain. The nerve cells show a very low carbonic anhydrase activity. This specific localization supports the view that glial carbonic anhydrase is implicated in a mechanism for the active transport of chloride from the capillaries to the interstitial and cerebrospinal fluids.Keywords
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