Acute Coronary Insufficiency and Potential Cardiac Work

Publisher Website
Google Scholar
Abstract
The left anterior descending and right coronary arteries were acutely ligated in anesthetized open chest dogs. Strain gauge arches were sutured to the myocardium for the measurement of isometric tension changes of the normal myocardium as well as the ischemic area. The changes in tension accompanying ligation indicate that the left coronary arterial tree is predominant in the dog and quite often supplies blood to a,large area of the right ventricle. However, in several animals, from the developed tension produced by normal and ischemic areas of the myocardium, there seemed to exist some bizarre patterns of coronary distribution. An absence of a decrease in myocardial tension in the predicted ischmeic zone was observed in several experiments. This may be due either to the presence of interarterial coronary anastomoses or to an anatomic variation in the coronary artery pattern. During ligation there sometimes occurred an increment in tension developed by the normal myocardium which may be a compensating mechanism for failure of the ischemic area.