Secondary malignant neoplasms in patients with Hodgkin's disease
- 9 June 1978
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 239 (23) , 2470-2471
- https://doi.org/10.1001/jama.239.23.2470
Abstract
Retrospective analysis of 232 cases of Hodgkin''s disease (HD) treated at the University of Manitoba [Canada] from Jan. 1, 1965, to Dec. 31, 1973, and followed up to 44.3 mo. disclosed 5 cases of secondary malignant neoplasms. Two cases of acute leukemia were discovered compared with an expected value of 0.05. All neoplasms developed in the mixed cellularity group, representing only 28% of the HD cases. Combinations of radiotherapy and chemotherapy may have increased the incidence of leukemia, but its frequency does not appear high enough to abandon combined modality treatment.This publication has 1 reference indexed in Scilit:
- Sequential Radiotherapy and Chemotherapy in the Treatment of Hodgkin's DiseaseAnnals of Internal Medicine, 1972