FACTORS CONCERNED IN POSITIONAL ALTERATIONS OF INTRACRANIAL PRESSURE

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Abstract
An analysis of the factors concerned in the pressure-alterations in the cerebrospinal fluid, induced by abrupt changes of the animal''s position, has been made from data gathered from living etherized dogs subjected to different experimental procedures (intact, trephined, laminectomized throughout lumbar and thoracic regions, spinal cord ligated in upper thoracic region) and from dead dogs of similar size (immediately after death, one week after death, and those with complete gelatine injections of the vascular channels). The suggestion is put forward that the two factors concerned- meningeal and vascular-are not additive in final effect upon the pressure-change in the cerebrospinal fluid, but that the pressure-change recorded under conditions of minimal volume-dislocation may be determined solely by one of these two factors.

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