Temperature Dependence of ADH-Induced Water Flow and Intramembranous Particle Aggregates in Toad Bladder

Publisher Website
Google Scholar
Abstract
Antidiuretic hormone (ADH)-induced luminal intramembranous particle aggregates and hormonally stimulated water flow in toad urinary bladder are reduced simultaneously with a reduction in temperature. When water movement is factored by the aggregation response, the apparent activation energy for this process decreases from 12.1 ± 1.6 to 3.0 ± 2.3 kilocalories per mole. The data are consistent with the view that the particle aggregates contain sites for transmembrane water movement and that these sites behave as pores.