PARallels in Axis Formation
- 9 June 2000
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 288 (5472) , 1759-1760
- https://doi.org/10.1126/science.288.5472.1759
Abstract
There is an intricate network of molecules called cell fate determinants that instruct the cells of the embryo to take on either an anterior or posterior fate. In a lively Perspective, Lehmann and her colleagues discuss new findings in the fruit fly that identify a key protein, PAR-1, which ensures that the cell fate determinants are themselves located in the correct region of the oocyte. In this way, the anterior-posterior axis is set up in the fruit fly egg before fertilization.Keywords
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