LASER VAPORIZATION IN THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA

  • 1 January 1985
    • journal article
    • research article
    • Vol. 30  (3) , 179-183
Abstract
Ablative cryotherapy and laser vaporization therapy attempt to eradicate the cervical transformation zone in order to eliminate cervical intraepithelial neoplasia and to reduce the risk of invasive cancer. The literature on both methods and experience with laser therapy were reviewed. Review of the records of 4557 initial cryosurgical patients as compared to those of 1505 initial laser patients revealed cure rates of 12% and 13.8%, respectively (no significant difference, P > 0.14). Multiple treatments in 533 cryosurgery and 1775 laser patients revealed cure rates of 11 and 2.6%, respectively (P < 0.0001). Enhanced accessibility of the new squamocolumnar junction following laser surgery may result in improved early detection of initial treatment failures and significantly improve the success rates of retreatment. If so, a reduction in the development of invasive cancer in laser-treated patients may occur.