Anorectic Effect of Chlordimeform in the American Cockroach1

Publisher Website
Google Scholar
Abstract
Chlordimeform and several other neuroactive amines were assayed for anorectic activity in starved American cockroaches, Periplaneta Americana (L.). Of 9 compounds tested, chlordimeform was the most potent, causing a 78% reduction in food consumption after a dose of 1 μg. Octopamine also was a potent anorexigenic agent, whereas the octopamine analogue isoproterenol was devoid of anorectic activity. No correlation existed between anoretic potency and either acute toxicity, monoamine oxidase inhibitory activity, or local anaesthetic activity.

This publication has 0 references indexed in Scilit: