Mutagenicity of Experimental Inhalational Anesthetic Agents
Open Access
- 1 June 1982
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 56 (6) , 462-463
- https://doi.org/10.1097/00000542-198206000-00011
Abstract
A modification of the Ames bacterial assay system employing 2 histidine-dependent strains of Salmonella typhimurium, TA1535 and TA100, was used to test the mutagenicity [potential carcinogenicity] of 4 experimental, inhalational anesthetic agents: sevoflurane, synthane, dioxychlotrane and dioxyflurane. None of the anesthetics was mutagenic. Increased activity was seen only with vinylidene chloride, the positive control.This publication has 0 references indexed in Scilit: