Drug discovery and drug metabolism
- 31 May 1996
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 1 (5) , 209-216
- https://doi.org/10.1016/1359-6446(96)10017-9
Abstract
No abstract availableThis publication has 30 references indexed in Scilit:
- Biopharmaceutical R&D Success Rates and Development TimesNature Biotechnology, 1994
- Selective Inhibitors of Cytochromes P450Toxicology and Applied Pharmacology, 1994
- The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and NomenclatureDNA and Cell Biology, 1993
- In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug DevelopmentDrug Metabolism Reviews, 1993
- Recombinant DNA approaches for the development of metabolic systems used in in vitro toxicologyMutation Research/Reviews in Genetic Toxicology, 1992
- Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxideChemical Research in Toxicology, 1992
- Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobioticsBiochemical Journal, 1992
- Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactionsChemical Research in Toxicology, 1992
- New drug development in the United States from 1963 to 1990Clinical Pharmacology & Therapeutics, 1991
- Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including manXenobiotica, 1986