Reactive Oxygen Species and Aging: Evolving Questions
- 29 June 2005
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science of Aging Knowledge Environment
- Vol. 2005 (26) , pe20
- https://doi.org/10.1126/sageke.2005.26.pe20
Abstract
Over the past 50 years, reactive oxygen species (ROS) have been investigated as putative mediators of the process of aging. As specific genes and pathways that are involved with ROS homeostasis have been linked to aging in lower organisms, such as Caenorhabditis elegans and Drosophila , the questions of how ROS regulate aging in higher organisms, and whether they do so to the same extent as in lower organisms, have emerged.Keywords
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