Effects of Prolonged Isolation of the Skin on Cutaneous Sensitivity

Abstract
Isolation of a circumscribed area of the skin on the forearm for a week resulted in an increase in tactual acuity. Application of constant pressure to the same area resulted in decreased tactual acuity. These changes were still evident two days after the experiment. It is believed that central rather than peripheral factors are responsible for these changes. Temperature and pain sensitivity were not affected.
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