Studying plasmid horizontal transfer in situ: a critical review
Top Cited Papers
- 1 September 2005
- journal article
- review article
- Published by Springer Nature in Nature Reviews Microbiology
- Vol. 3 (9) , 700-710
- https://doi.org/10.1038/nrmicro1232
Abstract
This review deals with the prospective, experimental documentation of horizontal gene transfer (HGT) and its role in real-time, local adaptation. We have focused on plasmids and their function as an accessory and/or adaptive gene pool. Studies of the extent of HGT in natural environments have identified certain hot spots, and many of these involve biofilms. Biofilms are uniquely suited for HGT, as they sustain high bacterial density and metabolic activity, even in the harshest environments. Single-cell detection of donor, recipient and transconjugant bacteria in various natural environments, combined with individual-based mathematical models, has provided a new platform for HGT studies.Keywords
This publication has 109 references indexed in Scilit:
- The outs and ins of bacterial type IV secretion substratesTrends in Microbiology, 2003
- The versatile bacterial type IV secretion systemsNature Reviews Microbiology, 2003
- The Plasmid Genome DatabaseMicrobiology, 2003
- Ecological and molecular maintenance strategies of mobile genetic elementsFEMS Microbiology Ecology, 2002
- The ecology of transfer of mobile genetic elementsFEMS Microbiology Ecology, 2002
- Natural conjugative plasmids induce bacterial biofilm developmentNature, 2001
- Natural transformation competence in Helicobacter pylori is mediated by the basic components of a type IV secretion systemMolecular Microbiology, 2001
- Involvement of a Plasmid in Virulence of Campylobacter jejuni 81-176Infection and Immunity, 2000
- Paradigms of plasmid organizationMolecular Microbiology, 2000
- Retrotransfer or gene capture: a feature of conjugative plasmids, with ecological and evolutionary significanceMicrobiology, 1999