Kohlenmonoxydintoxikation: Bedeutung computer- und magnetresonanztomographischer kranieller Befunde für Klinik und Verlauf

Abstract
Clinical, CT and MR imaging findings of 5 patients are presented who suffered from sudden coma due to carbon monoxide intoxication. Follow-up investigations were done for up to three years. 4 patients recovered with only minor deficits, while one patient survived with a severe choreatic syndrome. Cranial computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated typical lesions in the globus pallidus, the cerebral white matter and the cortex. Initial lesions of the cerebral white matter rather than of the globus pallidus seem to indicate a doubtful clinical prognosis. In the CT of the severe case progressive white matter atrophy was visible still after half a year. In contrast, in two cases with good outcome repeated MRI showed no progressive white matter changes.

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