Biological True and False Serological Tests for Syphilis: Their Relationship with Anticardiolipin Antibodies
- 1 January 1990
- journal article
- research article
- Published by S. Karger AG in Dermatology
- Vol. 180 (3) , 151-153
- https://doi.org/10.1159/000248016
Abstract
Anticardiolipin antibodies (ACA) were determined by an ELISA assay in 142 VDRL-positive patients who were classified in two groups: group I consisted of 77 patients with syphilis and group II of 65 patients with biological false-positive reaction in the standard test for syphilis. In group I 10% had ACA versus 52% in group II (p < 0.0001). Isotype distribution in group II showed a predominance of IgG. These results suggest that antiphospholipid antibodies in VDRL and ACA tests have different specificities.Keywords
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