Brief Communication: Differential Susceptibility of Four Mouse Strains to Induction of Multiple Large-Bowel Neoplasms by 1,2-Dimethylhydrazine2
- 1 March 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 52 (3) , 999-1000
- https://doi.org/10.1093/jnci/52.3.999
Abstract
Weekly subcutaneous injections of 1,2 dimethylhydrazine into inbred ICR/Ha, randombred ICR/ Ha, C57BL/Ha, and DBA/2 mice produced tumors only in the ICR strains. Therefore, strain specificity of an organotropic chemical carcinogenesis model has been established.Keywords
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