The significance of colonic mucosa (intestinal metaplasia) involving the urinary tract
- 15 June 1987
- Vol. 59 (12) , 2086-2090
- https://doi.org/10.1002/1097-0142(19870615)59:12<2086::aid-cncr2820591220>3.0.co;2-j
Abstract
Although colonic type goblet cells are a relatively common component of reactive urothelial lesions and well-differentiated adenocarcinomas, complete replacement of areas of urothelium by benign appearing intestinal mucosa is a rare condition. All of the 11 documented cases occurred in association with abnormalities leading to chronic irritation and/or infection. In the three cases where the reported period of observation exceeded 2 years, all patients developed carcinoma. Despite its innocuous histology, widespread intestinal metaplasia apparently identifies a disturbed urothelium at high risk for cancer.This publication has 9 references indexed in Scilit:
- Villous Adenoma of the Urinary Bladder: A Morphologic or Biologic Entity?American Journal of Clinical Pathology, 1983
- Diffuse cystitis glandularis Associated with adenocarcinomatous changeUrology, 1980
- Unusual Bladder Mucosal Metaplasia In A Case Of Chronic Prostatitis And CystitisJournal of Urology, 1974
- Cystitis Glandularis and Adenocarcinoma of the BladderJournal of Urology, 1971
- Glandular neoplasia within the urinary tract. The aetiology of adenocarcinoma of the urothelium with a review of the literatureVirchows Archiv, 1971
- Intestinal metaplasia of the urinary tract epitheliumThe Journal of Pathology and Bacteriology, 1963
- Transition of Cystitis Glandularis to Primary Adenocarcinoma of the BladderJournal of Urology, 1958
- Metaplasia of Ureteral Epithelium Resulting in Intestinal Mucosa and Adenocarcinomatous Transformation: Report of Two CasesJournal of Urology, 1951
- Proliferation of Glands of the Urinary Bladder Simulating Malignant NeoplasmJournal of Urology, 1942