A Closer Look at Radiocontrast-Induced Nephropathy

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Abstract
Despite innovations in techniques of body imaging such as computerized radiography, ultrasonography, and magnetic resonance, the use of radiocontrast material is increasing, largely because of the need for angiography in connection with surgery or angioplasty on the coronary arteries, heart, and great vessels. The price exacted for the use of radiocontrast agents is the occasional and seemingly unpredictable occurrence of severe oliguric or nonoliguric acute renal failure. Even with optimal dialytic support, acute renal failure still involves substantial morbidity and mortality, for which prevention is more desirable (and more feasible) than the best therapy.1 In this issue of the Journal . . .