Sulfonylureas: a new class of cancer chemotherapeutic agents
- 1 August 1992
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 35 (16) , 3012-3016
- https://doi.org/10.1021/jm00094a013
Abstract
This study summarizes the antitumor properties of a number of sulofenur thiophene analogs against subcutaneously implanted 6C3HED lymphosarcoma with structural modification of the aryl moiety of the sulfonamide portion of the diarylsulfonylureas. The spectrum of activity of N-(p-chlorophenyl)-N'- [(5-methoxy-2-thienyl)sulfonyl]urea in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented.Keywords
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