Cutaneous protothecosis in a patient receiving immunosuppressive therapy

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Abstract
A 30 yr old recipient of a renal transplant, who was receiving immunosuppressive therapy [azathioprine and prednisolone], developed cutaneous abscesses from which a Prototheca organism was cultured. The patient died of Klebsiella septicemia. At the time of death, pure cultures of Prototheca and Candida were grown from separate skin lesions. Prototheca is a genus of achloric algae. Cultural, microscopic and staining characteristics separate these organisms from the yeast and fungi. Only 1 other case of protothecosis has been described in a patient receiving immunosuppressive drugs, a woman with breast carcinoma who was receiving chemotherapy with multiple agents.

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