Norepinephrine and 5-Hydroxytryptamine in the CNS of Rats under Continuous Illumination and Total Darkness

Abstract
Rats were subjected to DD [total darkness] and LL [continuous lumination] for a period of 30 days. Thereafter the NE [noreplnephrine] and 5HT concentration in the central nervous system (brain without plneal body) was determined. Both amine concentrations lie above those of animals living under a light-dark cycle. The motorically less active animals under LL show a higher increase of the 5HT [5-hydroxytryptamine] concentration, while the more active animals under DD show a higher increase of the NE concentration compared to the control groups. The quotient NE/5HT seems to be correlated with the level of motor activity of rats.