The distinction of corneal water in free and bound fractions
- 1 December 1982
- journal article
- research article
- Published by Springer Nature in Albrecht von Graefes Archiv für Ophthalmologie
- Vol. 219 (6) , 287-289
- https://doi.org/10.1007/bf00231415
Abstract
The corneal water is studied by NMR measurements. There are two fractions of water, one more strongly bound to relaxation centres of proteoglycanes and the other almost freely diffusible as liquid bulk water. A quantitative analysis shows that the bound fraction makes up a very small part (less than 1%) of the total water. So nearly all the water is available for the nutrition of the cornea by diffusion. Mittels NMR-Messungen wird das Corneawasser untersucht. Es zeigt sich, daß das Wasser in zwei Fraktionen aufgeteilt werden kann, von denen eine eng an Relaxationszentren der Proteoglykane gekoppelt ist, die andere nahezu frei diffusibel ist. Im Gegensatz zu anderen Meßmethoden zeigt eine quantitative Auswertung, daß der fest gebundene Anteil kleiner als 1% des Gesamtwassers ausmacht. Fast das gesamte Wasser steht also der Ernährung der Cornea als Diffusionsmedium zur Verfügung.This publication has 10 references indexed in Scilit:
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