Pimozide Treatment in Disruptive Severely Retarded Patients
- 1 March 1985
- journal article
- clinical trial
- Published by SAGE Publications in Australian & New Zealand Journal of Psychiatry
- Vol. 19 (1) , 92-94
- https://doi.org/10.3109/00048678509158820
Abstract
Eight severely retarded residents took part in a double blind, placebo controlled trial of pimozide. The drug did not alter behavioural adjustment as assessed by behaviour observations. However, ratings on a standardised checklist of aberrant behaviour showed significant drug-induced improvements on two dimensions (Irritability and Hyperactivity/non-compliance). Learning performance, as assessed by a discrimination learning task, was not affected by the drug.Keywords
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