It has been felt by numerous observers that malfunction of the liver plays a definite role in certain skin diseases. Stasis dermatitis has received the attention in this respect of several qualified authors, but most of them have been dermatologists. Since we felt that research into the relationship of liver disease and stasis dermatitis was a rather broad subject to be covered by one specialty, we decided to join our efforts on the problem. Stasis dermatitis is a chronic, subacute, or even acute, eczematoid dermatitis involving the lower legs and ankles. It is often accompanied by edema and sometimes by ulcers of the involved areas, and it is thought to result from an impairment of either or both the blood and the lymph circulation of the extremity. In most cases stasis dermatitis is due to varicose veins, and the condition clears when the veins have been treated adequately.1 However,