Progressive Decrease of Left Heschl Gyrus and Planum Temporale Gray Matter Volume in First-Episode Schizophrenia

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Abstract
THE HESCHL gyrus (HG) and the posteriorly adjacent planum temporale (PT) are located on the superior temporal gyrus (STG). The HG is primary auditory cortex (Brodmann area [BA] 41/42), playing a crucial role in auditory perception.1 The anterior portion of the PT is part of the unimodal auditory association cortex (part of BA22) that surrounds the HG, whereas the posterior portion adjacent to the temporoparietal junction (other portions of BA22 and part of BA39-40) is partially coextensive with the Wernicke area, consisting of heteromodal association cortex.2,3 The PT evinces the most prominent left-right asymmetry in the human brain,4 which is thought to reflect the critical role of PT in language processing.5

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