The direct agglutination test for chronic Chagas's disease. The effect of pre-treatment of test samples with 2-mercaptoethanol
- 1 January 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 75 (5) , 695-698
- https://doi.org/10.1016/0035-9203(81)90152-8
Abstract
The relative sensitivity and relative specificity of the direct agglutination (DA) test for the diagnosis of human Trypanosoma cruzi infection were studied in human serum samples, with and without previous treatment with 2-mercaptoethanol (2-ME), which were obtained from different areas of Brazil. Results obtained with these tests were related to those obtained with the indirect immunofluorescence (IIF) and indirect haemagglutination (IHA) tests. The DA test results from the sample not previously treated with 2-ME did not agree with those from the IIF and IHA tests. On the other hand, the DA test results from the sample previously treated with 2-ME agreed significantly (99·22%) with those from the IIF and IHA tests.Keywords
This publication has 3 references indexed in Scilit:
- Use of Micro-Elisa for Quantitating Antibody to Trypanosoma Cruzi and Trypanosoma Rangeli *The American Journal of Tropical Medicine and Hygiene, 1979
- Advances in the immunodiagnosis of parasitic infectionsZeitschrift Fur Parasitenkunde-Parasitology Research, 1974
- Trypanosoma cruzi: Agglutination activity of enzyme-treated epimastigotesExperimental Parasitology, 1971