Who needs a liver transplant? (new disease specific indications)

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Abstract
Individual cases of successful OLT are currently alive and well with normal liver functions up to 24 years after the procedure, but significant cohorts did not survive until cyclosporin A became generally available in 1986. Survival curves have steadily improved but retain the same basic characteristics—most mortality in the first three months and the slope almost horizontal by one year; thereafter, annual graft and patient loss are less than 1% and 0.5% respectively. Thus, the long term prognosis appears to be good following OLT (table1)1-16 but factors such as nephropathy and malignancy may have a much greater influence later in the course of follow up than our current experience.