MUTAGENESIS AND MORPHOLOGICAL TRANSFORMATION OF MAMMALIAN-CELLS BY A NON-BAY-REGION POLYCYCLIC CYCLOPENTA(CD)PYRENE AND ITS 3,4-OXIDE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 40  (12) , 4482-4484
Abstract
Cyclopenta(cd)pyrene, a constituent of environmental emissions, mutates and transforms mammalian [mouse] cells in culture. Cyclopenta(cd)pyrene 3,4-oxide, a presumed metabolite, was a direct-acting mutagen and to transform mammalian cells. Cyclopenta(cd)pyrene 3,4-oxide may be an ultimate mutagenic form of the parent hydrocarbon.