Nuclear Lipid Signaling: Novel Role of Eicosanoids
- 1 January 2001
- journal article
- review article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 226 (1) , 1-4
- https://doi.org/10.1177/153537020122600101
Abstract
Nuclear lipid signaling is an established, widespread mechanism that operates in multiple cellular processes including proliferative and differentiative responses to a variety of stimuli. In this literature review with key references highlighted, we put forward the hypothesis that differential flow through various intracrine mechanisms can dictate resultant cellular actions such as mitosis, differentiation, or apoptosis.Keywords
This publication has 36 references indexed in Scilit:
- Diacylglycerol – when is it an intracellular messenger?Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1998
- Acyl Chain Dependence of Diacylglycerol Activation of Protein Kinase C Activityin VitroBiochemical and Biophysical Research Communications, 1996
- Immunocytochemical detection of phosphatidylinositol 4,5-bisphosphate localization sites within the nucleus.Journal of Histochemistry & Cytochemistry, 1995
- .alpha.-Thrombin-induced nuclear sn-1,2-diacylglycerols are derived from phosphatidylcholine hydrolysis in cultured fibroblastsBiochemistry, 1994
- Phosphoinositidase C Isoforms Are Specifically Localized in the Nuclear Matrix and Cytoskeleton of Swiss 3T3 CellsExperimental Cell Research, 1993
- cPLA2 is phosphorylated and activated by MAP kinaseCell, 1993
- Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferatorsNature, 1990
- A novel phospholipase A2 associated with nuclear matrix: stimulation of the activity and modulation of the Ca2+ dependency by polyphosphoinositidesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1989
- Changes in nuclear inositol phospholipids induced in intact cells by insulin-like growth factor IBiochemical and Biophysical Research Communications, 1989
- Uptake and subcellular distribution of [3H]arachidonic acid in murine fibrosarcoma cells measured by electron microscope autoradiography.The Journal of cell biology, 1985