The assessment of drug treatment of spastic gait.
- 1 November 1981
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 44 (11) , 1035-1039
- https://doi.org/10.1136/jnnp.44.11.1035
Abstract
The technique of Polarized light goniometry was used to quantify objectively parameters of spastic gait in humans during a double-blind cross-over trial comparing the spasmolytic effects of DS103-282 [5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole hydrochloride] baclofen and placebo. Only minimal objective and subjective changes in gait were found when the results of treatment with DS103-282 or baclofen were compared with those of treatment with placebo.This publication has 5 references indexed in Scilit:
- Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.Journal of Neurology, Neurosurgery & Psychiatry, 1980
- C0-contraction and stretch reflexes in spasticity during treatment with baclofen.Journal of Neurology, Neurosurgery & Psychiatry, 1977
- An evaluation of baclofen treatment for certain symptoms in patients with spinal cord lesionsNeurology, 1976
- Clinical assessment and pharmacologic therapy of spasticity.1974
- Electromyographic recording of muscular activity in normal and spastic gaits.1952