Localization of the coagulation factor XIII B subunit gene (F13B) to chromosome bands 1q31?32.1 and restriction fragment length polymorphism at the locus
- 1 January 1989
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 81 (2) , 157-160
- https://doi.org/10.1007/bf00293893
Abstract
In situ hybridization of tritiated cDNA probes for the gene for the B subunit of coagulation factor XIII localized the F13B locus to bands q31–q32.1 on human chromosome 1 and perhaps more precisely to sub-bands 1q31.2 or 1q31.3. Restriction fragment length polymorphisms (RFLPs) were detected with BglII, EcoRI and XbaI. Because the RFLPs detected with each of the three enzymes were concordant in every individual studied and since each showed a similar size difference, it was concluded that the RFLPs probably result from an insertion or deletion of length approximately 0.37–0.4 kb.This publication has 18 references indexed in Scilit:
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