Differential Diagnosis of Infantile Hypotonia

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Abstract
During the past several years we have found electromyography and the Gesell developmental and neurologic examination to be of considerable help in the differential diagnosis of infantile hypotonia. We should like to present a preliminary report on the value of these diagnostic procedures. The publication of the papers of Werdnig,22Hoffmann,8and Oppenheim15first aroused interest in the problem of the differential diagnosis of infantile hypotonia. In the early part of this century many papers were written about the similarities and dissimilarities of Oppenheim's "amyotonia congenita," Werdnig and Hoffmann's "progressive spinal atrophy of infancy" and Turner's20"nonprogressive myopathy." Oppenheim described "amyotonia congenita" as a congenital diffuse muscular weakness with atrophy of the muscles and decreased or absent deep tendon reflexes that tended to improve. Werdnig-Hoffmann disease is similar, except that progressive weakness and deterioration occurs, usually leading to death by the age of 5 years, with

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