Histochemical Studies of Leukocytes from an Inflammatory Exudate

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Abstract
The activity of succinic dehydrogenase, mitochondrial [alpha]-glycerophosphate dehydrogenase, DPN diaphorase and TPN diaphorase was examined histochemically in inflammatory leukocytes obtained by the "skin window" technique. Different patterns of activity were observed with the different reactions, but the activity of all the enzymes was greater in the inflammatory leukocytes than in leukocytes from blood films. The results are discussed in terms of leukocyte metabolism, and it is concluded that the "mono-nuclear" cell types (lymphocytes, monocytes and macrophages) have a greater oxidative metabolism than granulocytes.