Diagnosis and Treatment of Primary Vaginal Carcinoma in Situ and Dysplasia

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Abstract
Fifteen cases of primary carcinoma in situ or severe or moderate dysplasia of the vagina were diagnosed and treated during the period of 1966-1975 in Finland. Because of abnormal vaginal cytology, the lesion was localized by means of colposcopy and I staining. For 6 patients, local estrogen treatment was applied to increase the thickness of the epidermal layer. For 6 patients, treatment consisted of simple excision. Nine patients, including both those with carcinoma in situ, were treated with intravaginal radiation therapy. The radiation dosage was 2000-2600 rad at a distance of 1 cm from the surface of the epithelium. None of the patients showed any complications; all are now symptom-free.

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