Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease
- 6 May 1999
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 340 (18) , 1398-1405
- https://doi.org/10.1056/nejm199905063401804
Abstract
Enterocutaneous fistulas are a serious complication of Crohn's disease and are difficult to treat. Infliximab, a chimeric monoclonal antibody to tumor necrosis factor α, has recently been developed as a treatment for Crohn's disease. We conducted a randomized, multicenter, double-blind, placebo-controlled trial of infliximab for the treatment of fistulas in patients with Crohn's disease.Keywords
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