Abstract
The need for more objectively quantifiable evaluation of the left ventricular function, obtainable on line with echocardiography, was fulfilled through modifications of integrated backscatter imaging to permit real‐time differentiation of the endocardium and the blood pool area in every image frame. Operator‐guided study of individual cardiac chambers permitted instantaneous measurement of chamber areas in either the systole or diastole, with resulting physiologically meaningful recordings that relate to cardiac function. Validation studies by various approaches suggest that the methodology is clinically relevant, and further improvements in design will sharpen its applicability in the future.

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