Outbreak of Canine Parvovirus Infection and Its Elimination in a Closed Beagle Dog Colony
Open Access
- 12 January 1987
- journal article
- research article
- Published by Wiley in Journal of Veterinary Medicine, Series B
- Vol. 34 (1-10) , 598-606
- https://doi.org/10.1111/j.1439-0450.1987.tb00440.x
Abstract
Summary: Severe canine parvovirus (CPV) infection occurred in a closed beagle dog colony. The infection was confirmed by virological, serological and histopathological examinations. Of 356 dogs, 188 (52.8%) showed clinical signs, 29 (8.1%) died, and 41 affected dogs (11.5%) were euthanized. Dogs of all ages became ill, but both the morbidity and mortality were highest in pups 3–4 months of age. Clinical signs were variable. Anorexia was most frequent, and other main signs were diarrhoea, depression and vomiting. Sudden death of pups due to myocarditis was not observed. When the disease ceased, nearly all the surviving dogs (98.0%) had HI antibody to CPV. In the dogs with high HI titres, the antibody persisted for at least 1.5 years. The virus was eliminated by intense disinfection, vaccination, cessation of mating and sacrifice of pups.Zusammenfassung: Ausbruch und Bekämpfung einer Parvovirus‐Infektion in einer geschlossenen Beagle‐KolonieIn einer geschlossenen Beagle‐Zucht traten schwer verlaufende Canine Parvovirus (CPV)‐Infektionen auf. Die klinischen Befunde wurden durch virologische, serologische und histopathologische Untersuchungen bestätigt. Von 356 Hunden zeigten 188 (52,8%) klinische Symptome, 29 (8,1%) verendeten und 41 erkrankte Hunde (11,5%) wurden euthanasiert. Es erkrankten Hunde aller Altersstufen, jedoch waren sowohl Morbidität als auch Mortalität bei den drei bis vier Monate alten Welpen am höchsten. Das klinische Bild war variabel; die Tiere zeigten am häufigsten Anorexie, daneben hauptsächlich Depression, Durchfall und Erbrechen. Durch Myokarditis verursachte plötzliche Todesfälle wurden nicht beobachtet. Nach Erlöschen der Krankheit hatten nahezu alle überlebenden Tiere (98,0%) Hah‐Antikörper gegen CPV. Bei Tieren mit hohen Hah‐Antikörper‐Titern waren nach mindestens 1,5 Jahren noch Antikörper zu finden. Viruselimination erfolgte durch intensive Desinfektion, Impfungen, Unterbrechung des Zuchtbetriebes und Keulung von Welpen.Keywords
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