Doxycycline‐resistant bacteria in periodontally diseased individuals after systemic doxycycline therapy and in healthy individuals

Publisher Website
Google Scholar
Abstract
The occurrence of doxycycline‐resistant bacteria was examined in subgingival Plaque and on the tonsils of 12 periodontally healthy and 12 periodontally diseased individuals. The healthy group was examined 6 times at intervals of One month. The diseased group was examined before and 1, 5, 15, 26, 39, and 52 weeks after conventional periodontal therapy supplemented with systemic doxycycline for 3 weeks. The occurrence of doxycycline‐resistant bacteria in the healthy group varied on average between 2.0% and 6.6% in subgingival plaque and Between 3.0% and 12.4% in the tonsil samples over a 6‐month period. In the Ceased group the percentage of resistant bacteria increased from 10–20 times Or tonsil and subgingival plaque, respectively. About half a year after therapy The values returned to the baselines. For both groups the morphological distributions of resistant bacteria were similar and unaffected by the doxycycline therapy.