Urinary Delta Amino-Laevulinic Acid and Porphobilinogen in Lead-Exposed Workers

Open Access
Publisher Website
Google Scholar
Abstract
Of 100 workers exposed to lead in varying degrees, 34 had a urinary delta amino-laevulinic acid (ALA) concentration of above 0·6 mg./100 ml. and a further 35 had an ALA concentration of between 0·3 mg. and 0·6 mg./100 ml. In only 20 of the workers was the urinary porphobilinogen concentration above 0·1 mg./100 ml., two of these being above 0·2 mg./100 ml. No significant correlation was found between the urinary concentration of ALA and coproporphyrin, nor was there correlation between the ALA and urinary lead levels, in fact the highest level of ALA was associated with a urinary lead of less than 200 μg./litre. A raised urinary lead was always associated with a raised ALA.

This publication has 14 references indexed in Scilit: