Effects of Short-Term and Subchronical Application of Fullerene C60Compound on Guinea Pig Isolated Myocyte Electrical Activity and Rat Chromaffin Cell Differentiation and Proliferation
- 1 September 1998
- journal article
- research article
- Published by Taylor & Francis in Fullerene Science and Technology
- Vol. 6 (5) , 815-825
- https://doi.org/10.1080/10641229809350242
Abstract
The ability of C60 to affect guinea pig myocyte electrical activity and rat chromaffin cell differentiation and proliferation was examined in vitro. C60 was dissolved with polyvinylpyrrolidone (PVP) in physiological solutions and short-term and subchronic application were carried out. No significant effects on electrical activity of isolated myocytes by short-term extracellular application and chromaffin cell differentiation and proliferation by subchronic application of C60 + PVP were observed. Possible therapeutic applications of this compound are discussed.Keywords
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