Studies on the Root Filling Cement Bi-Oxol.: A Clinical, Roentgenological and Histological Investigation

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Abstract
Twenty-five human incisors and canines with healthy pulps were used. Partial pulpectomy and subsequent root filling with Bi-oxol was performed in 11 cases, while in 14 cases the entire pulp was removed and the root filling material intentionally pushed through the foramen. The teeth were examined clinically and radiographically throughout the observation period, which varied from 2–to 32 1/2 months. Eighteen of these cases were also studied histologically. It was found that Bi-oxol in contact with vital tissue caused inflammation of varying extent. Gross overfilling resulted in more extensive inflammation than mere contact of the root filling material with the residual pulp. The root filling material was resorbed in the canal in cases of partial pulpectomy. Resorption was somewhat more rapid when the material was implanted in the periapical region. Granulation tissue invaded the canal to replace Bi-oxol. In cases of partial pulpectomy, no radiographic changes were recorded, whereas total pulpectomy with overfilling produced radiographic changes. Overfilling with severe inflammation observed histologically also gave clinical symptoms. The length of the residual pulp was found to be less in the sections than indicated by radiographs.

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