OBSERVATIONS ON THE HAEMOLYTIC ACTIVITY OF GUAIACOL GLYCEROL ETHER
Open Access
- 1 August 1963
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 35 (8) , 461-464
- https://doi.org/10.1093/bja/35.8.461
Abstract
The in vivo and in vitro haemolytic activity of guaiacol glycerol ether has been investigated. Intravenous injections in concentrations of 12.5 per cent or greater produced intravascular haemolysis. The haemolysis produced was not related to the speed of injection. In vitro studies with concentrations of guaiacol glycerol ether confirmed that the critical concentration for the production of haemolysis was 12.5 per cent. Guaiacol glycerol ether has approximately one-twentieth the haemolytic activity of ortho-toluol glycerol ether (mephenesin, Myanesin).Keywords
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