SWEATING PATTERNS IN THE SKIN FOLLOWING INJECTIONS OF MECHOLYL

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Abstract
The iodine-starch paper method was used in a study of sweating responses elicited by intra-dermal injns. of mecholyl (acetyl-/3-methyl choline chloride, Merck). Unique patterns of functioning sweat glands following mecholyl injns. suggested the participation of cutaneous lymph channels in convection of the drug away from the site of injn. These patterns consisted of narrow channels of sweat spots radiating outward from the wheal, being most prominent in a central direction, and apparently following the course of the lymphatic drainage. The probability of nervous participation in this type of spread of sweating response was negated.

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