Relief of persistent postamputation stump and phantom limb pain with intrathecal fentanyl
- 1 June 1989
- journal article
- research article
- Published by Wolters Kluwer Health in Pain
- Vol. 37 (3) , 317-322
- https://doi.org/10.1016/0304-3959(89)90197-8
Abstract
Two patients with postamputation stump and phantom limb pain respectively responded favorably to intrathecal fentanyl which temporarily abolished the pain, normalized sensations and produced euphoria without supraspinal effects. One of the patients subsequently received intrathecal, extradural and intravenous fentanyl as well as intrathecal lidocaine. The neuraxial (intrathecal and epidural) fentanyl temporarily abolished the pain. Intravenous fentanyl and intrathecal lidocaine were unable to reproduce this effect. Neuraxial fentanyl apparently produced its effects by a segmental spinal action. Spinal modulation of postamputation pain was important in these patients.This publication has 16 references indexed in Scilit:
- Phantom Limb Pain and Epidural Anesthesia for Cesarean SectionAnesthesiology, 1986
- Intrathecal Morphine and Heroin in HumansAnesthesia & Analgesia, 1986
- Phantom limb pain during spinal anaesthesiaAnaesthesia, 1983
- Phantom limb pain during peridural anaesthesiaPain, 1981
- Reorganisation of spinal cord sensory map after peripheral nerve injuryNature, 1978
- Phantom limbs and related phenomena in recent traumatic amputationsNeurology, 1978
- Phantom body pain in paraplegics: Evidence for a central “pattern generating mechanism” for painPain, 1977
- Observations on the Circulation of the Cerebrospinal FluidActa Radiologica. Diagnosis, 1966
- Movement of the Cerebrospinal Fluid in Human BeingsNature, 1964
- Theoretical Aspects of PainAnesthesiology, 1963