THE EFFECT OF HUMAN GONADOTROPHINS ON A PATIENT WITH SIMMONDS'S DISEASE

Publisher Website
Google Scholar
Abstract
A woman with Simmonds's disease which followed surgical removal of a pituitary tumour was treated with human pituitary follicle stimulating hormone and chorionic gonadotrophin. The treatment had no effect on her metabolic balances of nitrogen or electrolytes but caused a considerable increase in her excretion of oestriol with relatively little change in pregnanediol, a pattern associated with follicular development without ovulation. Changes in the timing of treatment with gonadotrophins and the addition of other hormones failed to alter this pattern, the nature and causes of which are discussed.

This publication has 2 references indexed in Scilit: