CORTISIM: A complex dynamical model of the cortisol regulation system
- 1 November 1986
- journal article
- Published by SAGE Publications in SIMULATION
- Vol. 47 (5) , 199-207
- https://doi.org/10.1177/003754978604700504
Abstract
The concept of complex dynamical systems is an outgrowth of the mathematical theory of nonlinear dynamical systems, devel oped in the context of physiological modeling. This paper de scribes an exemplary application of this new modeling strategy to the cortisol regulation system, along with some preliminary results of its simulation. The eventual intent of this project is the creation of a research tool for endocrine physiology.Keywords
This publication has 2 references indexed in Scilit:
- NEGATIVE, RATE-SENSITIVE FEEDBACK EFFECTS ON ADRENOCORTICOTROPHIN SECRETION BY CORTISOL IN NORMAL SUBJECTSJournal of Endocrinology, 1982
- Static gain and dynamics of cortisol secretory response to intravenous corticotropin (ACTH) in unanesthetized dogs analysis by a linear mean-squared estimatorAnnals of Biomedical Engineering, 1976